AnHeart Therapeutics
Dr. Seto has over 25 years of experience in oncology research specializing in medical oncology for thoracic malignancies. Conducting clinical trials with new agents has been his primary focus for the past 15 years at the National Kyushu Cancer Center. His tenure also includes Kumamoto Regional Medical Center and Tokai University Hospital. He joined Precision Medicine Asia (PREMIA) in September 2019 to focus on the development of precision medicine and targeted new drug therapies.
Dr. Seto is a member of the International Association for Study of Lung Cancer (IASLC, Board of Directors), the American Society for Clinical Oncology (ASCO), the European Society of Medical Oncology (ESMO), and the Japan Society of Medical Oncology (JSMO, Councilor), and the Japan Lung Cancer Society (JLCS, Councilor). In 2005, Dr. Seto was involved with the revision of the JLCS Practice Guideline and from 2014 to 2018, served as Chief of Medical Oncology and Multidisciplinary Therapy. He is also an active member of the Japan Clinical Oncology Group (JCOG) and a member and board member of the West Japan Oncology Group (WJOG).
Dr. Seto graduated from Kurume University School of Medicine in 1990.
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AnHeart Therapeutics
AnHeart Therapeutics (“AnHeart”) is a clinical-stage global biopharmaceutical company developing a broad pipeline of novel precision oncology therapeutics with high unmet medical needs. Its lead asset, taletrectinib, is a potential best-in-class next-generation ROS1 inhibitor currently in Phase 2 trials for ROS1 TKI-naïve and TKI-pretreated patients with ROS1 fusion-positive non-small cell lung cancer (NSCLC). Taletrectinib has received Breakthrough Therapy Designation (BTD) from both the US FDA and China NMPA for the treatment of patients with advanced or metastatic ROS1+ NSCLC, who are either ROS1 TKI treatment naïve or previously treated with crizotinib. The Company’s pipeline also includes AB-218, a mIDH1 inhibitor in Phase 2 trials with good brain penetration for multiple solid tumors with mIDH1 mutations and AB-329, an AXL inhibitor in Phase 1 studies to be used in combination with checkpoint inhibitor or chemotherapies in NSCLC or other solid tumors. The Company operates from offices in the US and China.