IGM Biosciences
Dr. Decker has served as the Chief Business Officer since 2021. Prior to joining IGM, Dr. Decker was Chief Business Officer at Atreca, where she led business development, including portfolio and alliance management functions. Dr. Decker has also served in multiple roles at Nektar Therapeutics, culminating in her final role as Vice President, Business Development, where she led all partnering activities including strategy, identifying and assessing new opportunities and developing deal structures and financial terms. She began her career in business development at the University of Massachusetts Medical School, where she was responsible for licensing, intellectual property strategy and management, and marketing of early stage life science inventions, including the University’s Nobel Prize winning RNAi technology. Dr. Decker received a Ph.D. in Immunology from Tufts University School of Medicine and a B.A. in Biology from the College of the Holy Cross.
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IGM Biosciences
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IGM Biosciences (Nasdaq: IGMS) is a clinical-stage biotechnology company focused on creating and developing engineered IgM antibodies. IgM antibodies have inherent properties that we believe may enable them to improve upon the efficacy and safety of IgG antibodies in multiple therapeutic applications. We have created a proprietary IgM antibody technology platform that we believe is particularly well suited for developing T cell engagers, receptor cross-linking agonists, and targeted cytokines. Our lead product candidate, IGM-2323, is a bispecific T cell engaging IgM antibody targeting CD20 and CD3, and we have initiated a Phase 1 clinical trial for the treatment of relapsed/refractory B cell Non-Hodgkin's lymphoma (NHL) patients in 2019. Our second product candidate is IGM-8444, an IgM antibody targeting Death Receptor 5 (DR5) for the treatment of patients with solid and hematologic malignancies, for which we have recently initiated a Phase 1 clinical trial. Also in our product pipeline is IGM-7354, a bispecific IgM antibody delivering interleukin-15 (IL-15) cytokines to PD-L1 expressing cells for the treatment of patients with solid and hematologic malignancies.