Kesmalea Therapeutics
Justin Bower is an experienced professional in drug discovery and medicinal chemistry. Justin has held various leadership roles in companies like Kesmalea Therapeutics, Cancer Research UK, AstraZeneca, and Vernalis. Justin has a PhD in Organic Synthetic Methodology from Loughborough University and has also worked as a Post Doc at the University of Waterloo in Canada. Justin is known for their expertise in leading teams of chemists and driving the delivery of drug discovery projects.
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Kesmalea Therapeutics
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Kesmalea is creating a new generation of protein homeostasis modulators, with a unique chemistry platform technology and therapeutic paradigm. Our novel approach allows us to overcome the challenges of existing protein degradation and stabilisation technologies, opening the door to previously unavailable oral therapeutics in areas of high unmet medical need. Protein homeostasis is the system of maintaining the equilibrium of proteins in the human body. This intricate system is in a constant state of change, with the body continuously synthesising and regulating proteins, whilst removing those which are no longer required (or have mutated) through controlled degradation. Small perturbations of the human body’s natural control mechanism that result in an excess or absence of certain proteins can drive the progression of disease. At Kesmalea, we’re aiming to counter this dysregulation with novel treatments which restore balance through effective protein degradation or stabilisation.