Xue Fei

Xue Fei has extensive experience in the field of structural biology. Xue is currently working at Kymera Therapeutics as a Principal Scientist, where they are responsible for leading multiple projects and delivering protein/protein-small molecule co-crystal structures. Xue has also established cryo-EM capability and determined ternary complex structures. Additionally, they have developed crystal systems for fragment screening using X-ray and has managed various teams for protein production and structure determination.

Prior to their current role, Xue Fei worked as a Senior Scientist at Kymera Therapeutics, where they played a key role in structural biology and lead discovery and optimization. Xue managed multiple CRO teams and contributed to the establishment of cryo-EM capability.

Before joining Kymera Therapeutics, Xue Fei was a Postdoctoral Fellow at the Massachusetts Institute of Technology (MIT), where they focused on the structural biology of AAA+ proteases. Xue reconstructed cryo-EM maps and elucidated the structural basis for ssrA degron recognition.

Xue Fei also worked as a Graduate Assistant at the University of Maryland, where they conducted structural-based studies on the mechanism of the molecular chaperone GroEL. Xue determined crystal structures of GroEL-ADP and GroEL-GroES "football" complex.

Lastly, Xue Fei had a brief research role at Baylor College of Medicine.

Xue Fei completed a Bachelor of Science (BS) degree in Biochemistry, Biophysics and Molecular Biology from the University of Science and Technology of China between the years 2005 and 2009. Following this, Xue Fei pursued a Doctor of Philosophy (Ph.D.) in Biophysics at the University of Maryland from 2009 to 2014.