David Wishart

Chief Physics Officer at ProMIS Neurosciences

Dr. David Wishart is a Distinguished University Professor in the Departments of Biological Sciences and Computing Science at the University of Alberta. He also holds adjunct appointments with the Faculty of Pharmaceutical Sciences and with the Department of Pathology and Laboratory Medicine. He has been with the University of Alberta since 1995. Dr. Wishart has been studying protein folding and misfolding for more than 30 years using a combination of computational and experimental approaches. These experimental approaches include NMR spectroscopy, circular dichroism, fluorescence spectroscopy, electron microscopy, protein engineering and molecular biology. The computational methods include molecular dynamics, agent-based modeling, bioinformatics and machine learning.

Over the course of his career, Dr. Wishart has published more than 430 scientific papers covering many areas of protein science including structural biology, protein metabolism and computational biochemistry. These papers have been cited more than 78,000 times. Dr. Wishart has been awarded research grants totaling more than $130 million from a number of funding agencies including CIHR, NSERC, NIH, Genome Canada, CFI, NRC, APRI, PrioNET, PENCE and Compute Canada. Dr. Wishart has also led or directed a number of core facilities and centres including the Canadian Bioinformatics Help Desk, the PENCE bioinformatics core facility, the NRC Nano Life Sciences Division, the PrioNet Prion Protein and Plasmid Production Facility, and the Pan-Alberta Metabolomics Platform (PANAMP).

Dr. Wishart currently co-directs The Metabolomics Innovation Centre (TMIC), Canada’s national metabolomics laboratory. Dr. Wishart held the Bristol-Myers Squibb Research Chair in Pharmaceutical Sciences from 1995-2005, received the Astra-Zeneca-CFPS Young Investigator Prize in 2001, was awarded a Lifetime Honorary Fellowship by the Metabolomics Society in 2014 and elected as a Fellow of the Royal Society of Canada in 2017. Dr. Wishart has been identified as one of the world’s most highly cited scientists for each of the past 7 years.


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ProMIS Neurosciences

ProMIS™ Neurosciences, Inc. is a development-stage biotech company that discovers and develops precision therapeutics and companion diagnostics for early detection and effective treatment of neurodegenerative diseases, in particular, Alzheimer’s disease (AD) and amyotrophic lateral sclerosis (ALS).


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Headquarters

Toronto, Canada

Employees

11-50

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