Walter Reed Army Institute of Research
Ramesh Marasini, Ph.D. has a diverse work experience in the field of gene therapy, mRNA-LNP formulation, drug formulation and delivery, and cell therapy. Ramesh has held various roles in different organizations since 2016. Ramesh started their career as a Graduate Researcher at Kansas State University, where they worked on lipid nanoparticles, exosomes, biomaterials, drug delivery, and theranostics. Following this, they worked at Johns Hopkins Medicine as an MSCRF Research Fellow, focusing on drug formulation and delivery, cell therapy, exosomes, and diagnostic imaging. Ramesh then joined ARV Technologies Inc. as a Scientist I, specializing in gene therapy, mRNA-LNP formulation, analytical development, and delivery. Currently, they are working at the Walter Reed Army Institute of Research as a Scientist, leading the mRNA-LNP drug development efforts, including plasmid production, encapsulation into lipid nanoparticles, downstream purification, and in-process analytical testing. Ramesh Marasini has demonstrated expertise in cGMP manufacturing, process development, process characterization, and process optimization in the field of gene and cell therapy.
Ramesh Marasini, Ph.D. obtained a Master of Science degree in Organic Chemistry and Natural Product Chemistry from Tribhuvan University, during the period of 2010 to 2013. Subsequently, they pursued a Doctor of Philosophy (PhD) in Biological Chemistry with a focus on Lipid Polymer Nanoparticles, Drug Delivery, Exosomes, and Molecular Imaging at Kansas State University, from 2016 to 2020. In 2021, they completed a Postgraduate Degree in Biomedical/Medical Engineering from The Johns Hopkins University.
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Walter Reed Army Institute of Research
WRAIR provides unique research capabilities and innovative medical solutions to a range of Force Health Protection and Readiness challenges currently facing U.S. Service Members, along with threats anticipated during future operations. Through both times of peace and war, infectious diseases have killed, sickened, and disabled far more Service Members than bombs and bullets. WRAIR has created a model of vaccine and therapeutic development that is unique, nimble, and responsive to dynamically evolving infectious disease threats of military importance. WRAIR, with its unparalleled expertise, facilities, and international network, has developed many vaccines and drugs in use today by military and civilian medicine around the globe. In addition to protecting against infectious disease threats, WRAIR conducts basic and applied research that promotes psychological resilience, enhances neurological functioning, and improves operational readiness among U.S. Service Members. By using a continuum of research from basic science to applied field studies, WRAIR creates innovative solutions to enhance Service Members’ resilience and recovery. Research in military psychiatry and neuroscience has been an integral part of WRAIR's portfolio for more than 70 years. WRAIR researchers are recognized leaders in operational medical research for the military in a number of fields, including brain trauma, blast exposure, deployment stressors, and sleep management.