Siyu Feng, PhD, currently serves as a Senior Scientist at BridgeBio Oncology Therapeutics, leading the cell biology team for the discovery and development of novel small molecule inhibitors within the “PI3Ka:RAS Breaker” program. Previously, Siyu held positions as a Senior Scientist and Scientist at BridgeBio, where significant contributions included conducting IND enabling studies and leading cell biology initiatives. Earlier experience includes a postdoctoral fellowship at Genentech, where Siyu utilized advanced techniques in gene engineering and bioinformatics to target oncogenic drivers. Siyu also participated as a finalist in the Merck Biopharma Innovation Cup and gained research experience as a graduate student researcher at the University of California, San Francisco, focusing on innovative protein technologies and cancer signaling mechanisms. Educational background comprises a dual PhD in Bioengineering and Biomedical Engineering from the University of California, San Francisco, and the University of California, Berkeley, complemented by a Bachelor's degree from Beihang University.
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BridgeBio Oncology Therapeutics (BBOT)
BridgeBio Oncology Therapeutics is a clinical-stage biopharmaceutical company advancing a next generation pipeline of novel small molecule therapeutics targeting RAS and PI3K malignancies. Initially formed as a subsidiary of BridgeBio, BridgeBio Oncology Therapeutics completed a $200M private financing with external investors in 2024 with the goal of improving outcomes for patients with cancers driven by the two most prevalent oncogenes in human tumors.