David Fajgenbaum

Co-founder at Every Cure

David Fajgenbaum, MD, MBA, MSc, serves as an Associate Professor of Medicine in Translational Medicine & Human Genetics at the University of Pennsylvania School of Medicine, recognized as one of the youngest tenured professors in Penn Medicine's history. Fajgenbaum is the founding director of the Center for Cytokine Storm Treatment & Laboratory and leads a 15-member translational research laboratory, while also holding positions as Associate Director of Patient Impact at the Penn Orphan Disease Center and on the Leadership Council of the Colton Center for Autoimmunity. With over 75 published papers and more than $16 million in research funding, Fajgenbaum has advanced 16 repurposed treatments. In addition, Fajgenbaum co-founded Every Cure and serves as a board member for Creyon Bio and the Reagan-Udall Foundation for the FDA. Fajgenbaum also co-founded and presides over the Castleman Disease Collaborative Network and previously co-founded the National Students of AMF Support Network. Academic credentials include an MD from the University of Pennsylvania School of Medicine, an MBA from The Wharton School, and an MSc from the University of Oxford.

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Philadelphia, United States

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Every Cure

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Every Cure is a nonprofit organization dedicated to unlocking the full potential of every existing medicine to treat every disease possible. Repurposing existing drugs is the fastest and most efficient way to treat diseases with the greatest return on investment for saving lives. However, systemic barriers impede repurposing, so patients suffer while potential treatments are not fully utilized. Every Cure overcomes these barriers to systematically identify and advance promising repurposing opportunities and save lives. Every Cure is taking a revolutionary and disruptive approach to overcome these systemic barriers by developing a comprehensive, open-source data engine to generate predictive efficacy scores for all 3,000 drugs against all 12,000 diseases and rapidly advance treatments to patients. In partnership with academia, industry, and government, Every Cure is integrating proprietary and public data into a comprehensive dataset, optimizing AI ranking algorithms, validating the most promising drug-disease matches, performing trials, and ensuring patient access to effective therapies.


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