Dewpoint Therapeutics
Alex Holehouse is an assistant professor in the Department of Biochemistry and Molecular Biophysics at Washington University School of Medicine, where his lab leverages a range of computational and experimental approaches to understand how disordered proteins mediate biological function. In particular, the lab integrates physics-based models with informatics and machine learning, with a major focus on understanding how disordered proteins contribute to cellular information-processing, and how this can go awry in disease.
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Dewpoint Therapeutics
Dewpoint Therapeutics is the first company founded to apply the emerging discipline of biomolecular condensates to drug discovery. Dewpoint believes that a vast range of conditions has pathways that are regulated by condensates or arise from the dysfunction of condensates - including cancer, neurodegeneration, and metabolic disease.