IGM Biosciences
Dr. Ahmed is a virologist and immunologist, and an internationally recognized expert on T cell survival, function and the development of immunological memory. He is a Director of the Emory Vaccine Center; Charles Howard Candler Professor of Microbiology and Immunology, Emory University School of Medicine. His work includes discoveries related to how immune memory cells are created, how long they survive and how factors such as IL-2 and IL-15 relate to these responses within different microenvironments within an organism and the relationship between chronic viral infection and ongoing immunity. His work impacts the development of therapeutics in infectious disease, particularly in the setting of viral infection and viral persistence to cancer and cancer immunology. Dr. Ahmed is the author or co-author of more than 300 peer-reviewed articles, has received numerous awards, including the William B. Coley Award in 2017 and is a member of the National Academy of Sciences. Dr. Ahmed received his Ph.D. degree in microbiology from Harvard University. Before coming to Emory, he was a Professor at the University of California, Los Angeles School of Medicine.
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IGM Biosciences
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IGM Biosciences (Nasdaq: IGMS) is a clinical-stage biotechnology company focused on creating and developing engineered IgM antibodies. IgM antibodies have inherent properties that we believe may enable them to improve upon the efficacy and safety of IgG antibodies in multiple therapeutic applications. We have created a proprietary IgM antibody technology platform that we believe is particularly well suited for developing T cell engagers, receptor cross-linking agonists, and targeted cytokines. Our lead product candidate, IGM-2323, is a bispecific T cell engaging IgM antibody targeting CD20 and CD3, and we have initiated a Phase 1 clinical trial for the treatment of relapsed/refractory B cell Non-Hodgkin's lymphoma (NHL) patients in 2019. Our second product candidate is IGM-8444, an IgM antibody targeting Death Receptor 5 (DR5) for the treatment of patients with solid and hematologic malignancies, for which we have recently initiated a Phase 1 clinical trial. Also in our product pipeline is IGM-7354, a bispecific IgM antibody delivering interleukin-15 (IL-15) cytokines to PD-L1 expressing cells for the treatment of patients with solid and hematologic malignancies.